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Induction of Cell Death by Betulinic Acid through Induction of Apoptosis and Inhibition of Autophagic Flux in Microglia BV-2 Cells
Betulinic acid (BA), a natural pentacyclic triterpene found in many medicinal plants is known to have various biological activity including tumor suppression and anti-inflammatory effects. In this study, the cell-death induction effect of BA was investigated in BV-2 microglia cells. BA was cytotoxic...
Autores principales: | Seo, Jeongbin, Jung, Juneyoung, Jang, Dae Sik, Kim, Joungmok, Kim, Jeong Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685431/ https://www.ncbi.nlm.nih.gov/pubmed/28274097 http://dx.doi.org/10.4062/biomolther.2016.255 |
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