Lipoprotein(a)-Associated Molecules Are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

The LPA gene is the only monogenetic risk factor for calcific aortic valve stenosis (CAVS). Oxidized phospholipids (OxPL) and lysophosphatidic acid generated by autotaxin (ATX) from OxPL are pro-inflammatory. Aortic valve leaflets categorized pathologically from both ATX–apolipoprotein B and ATX–apo...

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Detalles Bibliográficos
Autores principales: Torzewski, Michael, Ravandi, Amir, Yeang, Calvin, Edel, Andrea, Bhindi, Rahul, Kath, Stefan, Twardowski, Laura, Schmid, Jens, Yang, Xiaohong, Franke, Ulrich F.W., Witztum, Joseph L., Tsimikas, Sotirios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
CLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685511/
https://www.ncbi.nlm.nih.gov/pubmed/29147686
http://dx.doi.org/10.1016/j.jacbts.2017.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685511/
https://www.ncbi.nlm.nih.gov/pubmed/29147686
http://dx.doi.org/10.1016/j.jacbts.2017.02.004

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