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Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA(2) signalling

Lipopolysaccharide (LPS) from the cell envelope of Gram-negative bacteria is a principal cause of the symptoms of sepsis. LPS has been reported to modulate the function of platelets although the underlying mechanisms of LPS action in these cells remain unclear. Platelets express the Toll-like recept...

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Detalles Bibliográficos
Autores principales: Lopes Pires, Maria E., Clarke, Simon R., Marcondes, Sisi, Gibbins, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685579/
https://www.ncbi.nlm.nih.gov/pubmed/29136006
http://dx.doi.org/10.1371/journal.pone.0186981