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B cells regulate thymic CD8(+)T cell differentiation in lupus-prone mice

Previous studies have shown that under normal physiological conditions thymic B cells play a critical function in T cell negative selection. We tested the effect of thymic B cells on thymic T-cell differentiation in autoimmune diseases including systemic lupus erythematosus (SLE). We found that thym...

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Detalles Bibliográficos
Autores principales: Xing, Chen, Zhu, Gaizhi, Xiao, He, Fang, Ying, Liu, Xiaoling, Han, Gencheng, Chen, Guojiang, Hou, Chunmei, Shen, Beifen, Li, Yan, Ma, Ning, Wang, Renxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685686/
https://www.ncbi.nlm.nih.gov/pubmed/29163765
http://dx.doi.org/10.18632/oncotarget.19002