YAP1 is essential for tumor growth and is a potential therapeutic target for EGFR-dependent lung adenocarcinomas

Epidermal growth factor receptor (EGFR) mutations are found in lung adenocarcinomas leading to tumor cells proliferation and survival. EGFR tyrosine kinase inhibitors (TKIs) that block EGFR activity are effective therapeutics for EGFR-mutant lung adenocarcinoma patients, but TKI-resistance inevitabl...

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Detalles Bibliográficos
Autores principales: Lee, Ting-Fang, Tseng, Yu-Chi, Chang, Wei-Chin, Chen, Yi-Chen, Kao, Yu-Rung, Chou, Teh-Ying, Ho, Chao-Chi, Wu, Cheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685690/
https://www.ncbi.nlm.nih.gov/pubmed/29163769
http://dx.doi.org/10.18632/oncotarget.19647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685690/
https://www.ncbi.nlm.nih.gov/pubmed/29163769
http://dx.doi.org/10.18632/oncotarget.19647

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