Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling

The anti-apoptotic cellular FLICE-like inhibitory protein cFLIP plays a pivotal role in normal tissues homoeostasis and the development of many tumors, but its role in normal thymus (NT), thymomas and thymic carcinomas (TC) is largely unknown. Expression, regulation and function of cFLIP were analyz...

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Detalles Bibliográficos
Autores principales: Belharazem, Djeda, Grass, Albert, Paul, Cornelia, Vitacolonna, Mario, Schalke, Berthold, Rieker, Ralf J., Körner, Daniel, Jungebluth, Philipp, Simon-Keller, Katja, Hohenberger, Peter, Roessner, Eric M., Wiebe, Karsten, Gräter, Thomas, Kyriss, Thomas, Ott, German, Geserick, Peter, Leverkus, Martin, Ströbel, Philipp, Marx, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685693/
https://www.ncbi.nlm.nih.gov/pubmed/29163772
http://dx.doi.org/10.18632/oncotarget.15929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685693/
https://www.ncbi.nlm.nih.gov/pubmed/29163772
http://dx.doi.org/10.18632/oncotarget.15929

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