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Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients

Malignant pleural mesothelioma (MPM) is an aggressive cancer with an increasing incidence, poor prognosis and limited effective treatment options. Hence, new treatment strategies are warranted which include immune checkpoint blockade approaches with encouraging preliminary data. Research on the immu...

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Detalles Bibliográficos
Autores principales: Marcq, Elly, Waele, Jorrit De, Audenaerde, Jonas Van, Lion, Eva, Santermans, Eva, Hens, Niel, Pauwels, Patrick, van Meerbeeck, Jan P., Smits, Evelien L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685704/
https://www.ncbi.nlm.nih.gov/pubmed/29163783
http://dx.doi.org/10.18632/oncotarget.21113