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Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients
Malignant pleural mesothelioma (MPM) is an aggressive cancer with an increasing incidence, poor prognosis and limited effective treatment options. Hence, new treatment strategies are warranted which include immune checkpoint blockade approaches with encouraging preliminary data. Research on the immu...
Autores principales: | Marcq, Elly, Waele, Jorrit De, Audenaerde, Jonas Van, Lion, Eva, Santermans, Eva, Hens, Niel, Pauwels, Patrick, van Meerbeeck, Jan P., Smits, Evelien L.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685704/ https://www.ncbi.nlm.nih.gov/pubmed/29163783 http://dx.doi.org/10.18632/oncotarget.21113 |
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