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Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy

Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications. In advanced cancer, disease burden and cfDNA tumor content are often elevated, yielding unique precision oncology opportunities. We soug...

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Detalles Bibliográficos
Autores principales: Hovelson, Daniel H., Liu, Chia-Jen, Wang, Yugang, Kang, Qing, Henderson, James, Gursky, Amy, Brockman, Scott, Ramnath, Nithya, Krauss, John C., Talpaz, Moshe, Kandarpa, Malathi, Chugh, Rashmi, Tuck, Missy, Herman, Kirk, Grasso, Catherine S., Quist, Michael J., Feng, Felix Y., Haakenson, Christine, Langmore, John, Kamberov, Emmanuel, Tesmer, Tim, Husain, Hatim, Lonigro, Robert J., Robinson, Dan, Smith, David C., Alva, Ajjai S., Hussain, Maha H., Chinnaiyan, Arul M., Tewari, Muneesh, Mills, Ryan E., Morgan, Todd M., Tomlins, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685714/
https://www.ncbi.nlm.nih.gov/pubmed/29163793
http://dx.doi.org/10.18632/oncotarget.21163