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Oral 4-(N)-stearoyl gemcitabine nanoparticles inhibit tumor growth in mouse models

In spite of recent advances in targeted tumor therapy, systemic chemotherapy with cytotoxic agents remains a vital cancer treatment modality. Gemcitabine is a nucleoside analog commonly used in the treatment of various solid tumors, but an oral gemcitabine dosage form remain unavailable. Previously,...

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Detalles Bibliográficos
Autores principales: Wang, Caixia, Zheng, Yuanqiang, Sand oval, Michael A., Valdes, Solange A., Chen, Zhe, Lansakara-P, Dharmika S., Du, Maolin, Shi, Yanchun, Cui, Zhengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685716/
https://www.ncbi.nlm.nih.gov/pubmed/29163795
http://dx.doi.org/10.18632/oncotarget.21264