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Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer

Tumor-infiltrating T-cells are strongly associated with prognosis in colorectal cancer, but the mechanisms governing intratumoral lymphocyte recruitment are unclear. We investigated the clinical relevance and functional contribution of interferon-regulated CXC-chemokines CXCL9, CXCL10, and CXCL11, d...

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Detalles Bibliográficos
Autores principales: Kistner, Larissa, Doll, Dietrich, Holtorf, Anne, Nitsche, Ulrich, Janssen, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685727/
https://www.ncbi.nlm.nih.gov/pubmed/29163806
http://dx.doi.org/10.18632/oncotarget.21286