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CD4(+)T cell specific B7-H1 selectively inhibits proliferation of naïve T cells and Th17 differentiation in experimental autoimmune encephalomyelitis

It is widely acknowledged that interleukin 17-producing T helper (Th17) cells are critically participant in the pathogenesis of multiple sclerosis. In the current study, we identified that the expression of CD4(+)T cells specific co-inhibitory molecule B7-homologue 1(B7-H1) in spleenocytes and monon...

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Detalles Bibliográficos
Autores principales: Shi, Sheng-Jia, Ding, Mei-Ling, Wang, Li-Juan, Wu, Jie-Heng, Han, Dong-Hui, Zheng, Guo-Xu, Guo, Zhang-Yan, Xi, Wen-Jin, Qin, Wei-Jun, Yang, An-Gang, Wen, Wei-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685729/
https://www.ncbi.nlm.nih.gov/pubmed/29163808
http://dx.doi.org/10.18632/oncotarget.21357