Sestrin2 and sestrin3 suppress NK-92 cell-mediated cytotoxic activity on ovarian cancer cells through AMPK and mTORC1 signaling

Ovarian cancer is one of the major cancer types. NK-92 cell line, which has consistently and reproducibly high anti-tumor cytotoxicity, may be used for immunotherapy against ovarian cancer. Understanding the mechanisms that regulate the anti-tumor activity of NK-92 cells is important for developing...

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Detalles Bibliográficos
Autores principales: Wang, Xuejin, Liu, Weifeng, Zhuang, Deyi, Hong, Shaoxian, Chen, Jingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685737/
https://www.ncbi.nlm.nih.gov/pubmed/29163816
http://dx.doi.org/10.18632/oncotarget.21487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685737/
https://www.ncbi.nlm.nih.gov/pubmed/29163816
http://dx.doi.org/10.18632/oncotarget.21487

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