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Pediatric brain tumor cells release exosomes with a miRNA repertoire that differs from exosomes secreted by normal cells

High-grade gliomas (HGGs) are very aggressive brain tumors with a cancer stem cell component. Cells, including cancer stem cells, release vesicles called exosomes which contain small non-coding RNAs such as microRNAs (miRNAs). These are thought to play an important role in cell-cell communication. H...

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Detalles Bibliográficos
Autores principales: Tűzesi, Ágota, Kling, Teresia, Wenger, Anna, Lunavat, Taral R., Jang, Su Chul, Rydenhag, Bertil, Lötvall, Jan, Pollard, Steven M., Danielsson, Anna, Carén, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685739/
https://www.ncbi.nlm.nih.gov/pubmed/29163818
http://dx.doi.org/10.18632/oncotarget.21621