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Engineering Specificity and Function of Therapeutic Regulatory T Cells

Adoptive therapy with polyclonal regulatory T cells (Tregs) has shown efficacy in suppressing detrimental immune responses in experimental models of autoimmunity and transplantation. The lack of specificity is a potential limitation of Treg therapy, as studies in mice have demonstrated that specific...

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Detalles Bibliográficos
Autores principales: McGovern, Jenny L., Wright, Graham P., Stauss, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686054/
https://www.ncbi.nlm.nih.gov/pubmed/29176976
http://dx.doi.org/10.3389/fimmu.2017.01517