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Engineering Specificity and Function of Therapeutic Regulatory T Cells

Adoptive therapy with polyclonal regulatory T cells (Tregs) has shown efficacy in suppressing detrimental immune responses in experimental models of autoimmunity and transplantation. The lack of specificity is a potential limitation of Treg therapy, as studies in mice have demonstrated that specific...

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Detalles Bibliográficos
Autores principales:	McGovern, Jenny L., Wright, Graham P., Stauss, Hans J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686054/ https://www.ncbi.nlm.nih.gov/pubmed/29176976 http://dx.doi.org/10.3389/fimmu.2017.01517

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