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Engineering Specificity and Function of Therapeutic Regulatory T Cells
Adoptive therapy with polyclonal regulatory T cells (Tregs) has shown efficacy in suppressing detrimental immune responses in experimental models of autoimmunity and transplantation. The lack of specificity is a potential limitation of Treg therapy, as studies in mice have demonstrated that specific...
Autores principales: | McGovern, Jenny L., Wright, Graham P., Stauss, Hans J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686054/ https://www.ncbi.nlm.nih.gov/pubmed/29176976 http://dx.doi.org/10.3389/fimmu.2017.01517 |
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