Association of predicted pathogenic mutations in mitochondrial ND genes with distant metastasis in NSCLC and colon cancer

Cancer cells have more mutations in their mitochondrial DNA (mtDNA) than do normal cells, and pathogenic mutations in the genes encoding mitochondrial NADH dehydrogenase (ND) subunits have been found to enhance the invasive and metastatic ability of various tumour cells in animal experiments. Howeve...

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Detalles Bibliográficos
Autores principales: Koshikawa, Nobuko, Akimoto, Miho, Hayashi, Jun-Ichi, Nagase, Hiroki, Takenaga, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686070/
https://www.ncbi.nlm.nih.gov/pubmed/29138417
http://dx.doi.org/10.1038/s41598-017-15592-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686070/
https://www.ncbi.nlm.nih.gov/pubmed/29138417
http://dx.doi.org/10.1038/s41598-017-15592-2

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