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Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human Airway Epithelial Cells

The function of cystic fibrosis transmembrane conductance regulator (CFTR) channels is crucial in human airways. However unfortunately, chronic Pseudomonas aeruginosa infection has been shown to impair CFTR proteins in non-CF airway epithelial cells (AEC) and to alter the efficiency of new treatment...

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Detalles Bibliográficos
Autores principales: Maillé, Émilie, Ruffin, Manon, Adam, Damien, Messaoud, Hatem, Lafayette, Shantelle L., McKay, Geoffrey, Nguyen, Dao, Brochiero, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686086/
https://www.ncbi.nlm.nih.gov/pubmed/29177135
http://dx.doi.org/10.3389/fcimb.2017.00470