Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover

The critical mutation rate (CMR) determines the shift between survival-of-the-fittest and survival of individuals with greater mutational robustness (“flattest”). We identify an inverse relationship between CMR and sequence length in an in silico system with a two-peak fitness landscape; CMR decreas...

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Detalles Bibliográficos
Autores principales: Aston, Elizabeth, Channon, Alastair, Belavkin, Roman V., Gifford, Danna R., Krašovec, Rok, Knight, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686101/
https://www.ncbi.nlm.nih.gov/pubmed/29138394
http://dx.doi.org/10.1038/s41598-017-14628-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686101/
https://www.ncbi.nlm.nih.gov/pubmed/29138394
http://dx.doi.org/10.1038/s41598-017-14628-x

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