Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer

Small cell lung cancer (SCLC) is a difficult to treat subtype of lung cancer. One of the hallmarks of SCLC is its almost uniform chemotherapy sensitivity. However, chemotherapy response is typically transient and patients frequently succumb to SCLC within a year following diagnosis. We performed a t...

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Detalles Bibliográficos
Autores principales: Doerr, Fabian, George, Julie, Schmitt, Anna, Beleggia, Filippo, Rehkämper, Tim, Hermann, Sarah, Walter, Vonn, Weber, Jean-Philip, Thomas, Roman K., Wittersheim, Maike, Büttner, Reinhard, Persigehl, Thorsten, Reinhardt, H. Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686113/
https://www.ncbi.nlm.nih.gov/pubmed/29138515
http://dx.doi.org/10.1038/s41598-017-15840-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686113/
https://www.ncbi.nlm.nih.gov/pubmed/29138515
http://dx.doi.org/10.1038/s41598-017-15840-5

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