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SUMOylation regulates the localization and activity of Polo-like kinase 1 during cell cycle in the silkworm, Bombyx mori

Polo-like kinase 1 (Plk1) is a crucial cell cycle regulator by its specific localization and activity during cell cycle. It has been shown that the phosphorylation and ubiquitylation of Plk1 are required for its own activation and localization. Here, we report that SUMOylation regulates the activity...

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Detalles Bibliográficos
Autores principales: Li, Zhiqing, Cui, Qixin, Xu, Jian, Cheng, Daojun, Wang, Xiaoyan, Li, Bingqian, Lee, Jae Man, Xia, Qingyou, Kusakabe, Takahiro, Zhao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686133/
https://www.ncbi.nlm.nih.gov/pubmed/29138491
http://dx.doi.org/10.1038/s41598-017-15884-7