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Visualizing the GPCR Network: Classification and Evolution

In this study, we delineate an unsupervised clustering algorithm, minimum span clustering (MSC), and apply it to detect G-protein coupled receptor (GPCR) sequences and to study the GPCR network using a base dataset of 2770 GPCR and 652 non-GPCR sequences. High detection accuracy can be achieved with...

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Detalles Bibliográficos
Autores principales: Hu, Geng-Ming, Mai, Te-Lun, Chen, Chi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686146/
https://www.ncbi.nlm.nih.gov/pubmed/29138525
http://dx.doi.org/10.1038/s41598-017-15707-9