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Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway

Two hallmarks for cancer cells are the accelerated cell cycle progression as well as the altered metabolism, however, how these changes are coordinated to optimize the growth advantage for cancer cells are still poorly understood. Here we identify that Polo-like kinase 1 (Plk1), a key regulator for...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoyu, Wang, Lin, Huang, De, Li, Yunyan, Yang, Dongdong, Li, Tingting, Li, Fudong, Sun, Linchong, Wei, Haoran, He, Kun, Yu, Fazhi, Zhao, Debiao, Hu, Lan, Xing, Songge, Liu, Zhaoji, Li, Kui, Guo, Jing, Yang, Zhenye, Pan, Xin, Li, Ailing, Shi, Yunyu, Wang, Junfeng, Gao, Ping, Zhang, Huafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686148/
https://www.ncbi.nlm.nih.gov/pubmed/29138396
http://dx.doi.org/10.1038/s41467-017-01647-5