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The M25 gene products are critical for the cytopathic effect of mouse cytomegalovirus

Cell rounding is a hallmark of the cytopathic effect induced by cytomegaloviruses. By screening a panel of deletion mutants of mouse cytomegalovirus (MCMV) a mutant was identified that did not elicit cell rounding and lacked the ability to form typical plaques. Altered cell morphology was assigned t...

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Detalles Bibliográficos
Autores principales: Kutle, Ivana, Sengstake, Sarah, Templin, Corinna, Glaß, Mandy, Kubsch, Tobias, Keyser, Kirsten A., Binz, Anne, Bauerfeind, Rudolf, Sodeik, Beate, Čičin-Šain, Luka, Dezeljin, Martina, Messerle, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686157/
https://www.ncbi.nlm.nih.gov/pubmed/29138436
http://dx.doi.org/10.1038/s41598-017-15783-x