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Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos

Anterior–posterior (A–P) polarity of mouse embryos is established by distal visceral endoderm (DVE) at embryonic day (E) 5.5. Lefty1 is expressed first at E3.5 in a subset of epiblast progenitor cells (L1(epi) cells) and then in a subset of primitive endoderm cells (L1(dve) cells) fated to become DV...

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Detalles Bibliográficos
Autores principales: Takaoka, Katsuyoshi, Nishimura, Hiromi, Hamada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686177/
https://www.ncbi.nlm.nih.gov/pubmed/29138408
http://dx.doi.org/10.1038/s41467-017-01625-x