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Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos
Anterior–posterior (A–P) polarity of mouse embryos is established by distal visceral endoderm (DVE) at embryonic day (E) 5.5. Lefty1 is expressed first at E3.5 in a subset of epiblast progenitor cells (L1(epi) cells) and then in a subset of primitive endoderm cells (L1(dve) cells) fated to become DV...
Autores principales: | Takaoka, Katsuyoshi, Nishimura, Hiromi, Hamada, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686177/ https://www.ncbi.nlm.nih.gov/pubmed/29138408 http://dx.doi.org/10.1038/s41467-017-01625-x |
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