Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis

Sphingolipids regulate critical cellular processes including inflammation. Ceramide, which serves a central role in sphingolipid metabolism, is generated by six ceramide synthases (CerS) that differ in substrate specificity. CerS6 preferentially generates C(16)-ceramide and its mRNA is highly expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Scheffel, Matthew J., Helke, Kristi, Lu, Ping, Bowers, Jacob S., Ogretmen, Besim, Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Voelkel-Johnson, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686186/
https://www.ncbi.nlm.nih.gov/pubmed/29138469
http://dx.doi.org/10.1038/s41598-017-15791-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686186/
https://www.ncbi.nlm.nih.gov/pubmed/29138469
http://dx.doi.org/10.1038/s41598-017-15791-x

Ejemplares similares