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Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis

Sphingolipids regulate critical cellular processes including inflammation. Ceramide, which serves a central role in sphingolipid metabolism, is generated by six ceramide synthases (CerS) that differ in substrate specificity. CerS6 preferentially generates C(16)-ceramide and its mRNA is highly expres...

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Detalles Bibliográficos
Autores principales:	Scheffel, Matthew J., Helke, Kristi, Lu, Ping, Bowers, Jacob S., Ogretmen, Besim, Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Voelkel-Johnson, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686186/ https://www.ncbi.nlm.nih.gov/pubmed/29138469 http://dx.doi.org/10.1038/s41598-017-15791-x

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