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FOXA2 alleviates CCl(4)-induced liver fibrosis by protecting hepatocytes in mice

The liver-enriched transcription factor Forkhead Box A2 (FOXA2) has been reported to be involved in bile acid homeostasis and bile duct development. However, the role of FOXA2 in liver fibrogenesis remains undefined. In this study, we found that the abundance of FOXA2 was significantly lower in fibr...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Yao, Li-Jia, Shen, Weifeng, Ding, Kai, Shi, Pei-Mei, Chen, Fei, He, Jin, Ding, Jin, Zhang, Xin, Xie, Wei-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686201/
https://www.ncbi.nlm.nih.gov/pubmed/29138513
http://dx.doi.org/10.1038/s41598-017-15831-6