Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys

Kidney injury initiates metabolic reprogramming in tubule cells that contributes to the development of chronic kidney disease (CKD). Exercise has been associated with beneficial effects in patients with CKD. Here we show that the induction of a myokine, irisin, improves kidney energy metabolism and...

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Detalles Bibliográficos
Autores principales: Peng, Hui, Wang, Qianqian, Lou, Tanqi, Qin, Jun, Jung, Sungyun, Shetty, Vivekananda, Li, Feng, Wang, Yanlin, Feng, Xin-hua, Mitch, William E., Graham, Brett H., Hu, Zhaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686208/
https://www.ncbi.nlm.nih.gov/pubmed/29138395
http://dx.doi.org/10.1038/s41467-017-01646-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686208/
https://www.ncbi.nlm.nih.gov/pubmed/29138395
http://dx.doi.org/10.1038/s41467-017-01646-6

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