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Mnt modulates Myc-driven lymphomagenesis

The transcriptional represser Mnt is a functional antagonist of the proto-oncoprotein Myc. Both Mnt and Myc utilise Max as an obligate partner for DNA binding, and Myc/Max and Mnt/Max complexes compete for occupancy at E-box DNA sequences in promoter regions. We have previously shown in transgenic m...

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Detalles Bibliográficos
Autores principales: Campbell, Kirsteen J, Vandenberg, Cassandra J, Anstee, Natasha S, Hurlin, Peter J, Cory, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686348/
https://www.ncbi.nlm.nih.gov/pubmed/28800127
http://dx.doi.org/10.1038/cdd.2017.131