Eukaryotic-type serine/threonine kinase mediated phosphorylation at Thr(169) perturbs mycobacterial guanylate kinase activity

Guanylate kinase is an essential and conserved enzyme in nucleotide biosynthetic pathway that transfers phosphoryl group of ATP to GMP for yielding GDP. Here, we report the phosphorylation of guanylate kinase from Mycobacterium tuberculosis (mGmk) by eukaryotic-type Ser/Thr kinase, PknA. Mass spectr...

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Detalles Bibliográficos
Autores principales: S. Yadav, Ghanshyam, K. Ravala, Sandeep, Kachhap, Sangita, Thakur, Meghna, Roy, Abhishek, Singh, Balvinder, Karthikeyan, Subramanian, K. Chakraborti, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686395/
https://www.ncbi.nlm.nih.gov/pubmed/28963370
http://dx.doi.org/10.1042/BSR20171048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686395/
https://www.ncbi.nlm.nih.gov/pubmed/28963370
http://dx.doi.org/10.1042/BSR20171048

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