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Hypoxia induces the expression of TET enzymes in HepG2 cells

Hypoxia promotes tumor malignancy in solid tumors. One key mechanism by which this occurs is via epigenetic alteration. The present study demonstrates that hypoxia upregulates the expression of the ten-eleven-translocation 5-methylcytosine dioxygenase (TET) enzymes, which catalyze the conversion of...

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Detalles Bibliográficos
Autores principales: Lin, Guofu, Sun, Wenyu, Yang, Zhi, Guo, Jinshuai, Liu, Haiyang, Liang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686438/
https://www.ncbi.nlm.nih.gov/pubmed/29163682
http://dx.doi.org/10.3892/ol.2017.7063