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Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. These include a recent outbreak in the Caribbean islands and the Americas that caused more than 1 million cases of v...

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Detalles Bibliográficos
Autores principales: Jones, Jennifer E., Long, Kristin M., Whitmore, Alan C., Sanders, Wes, Thurlow, Lance R., Brown, Julia A., Morrison, Clayton R., Vincent, Heather, Peck, Kayla M., Browning, Christian, Moorman, Nathaniel, Lim, Jean K., Heise, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686535/
https://www.ncbi.nlm.nih.gov/pubmed/29138302
http://dx.doi.org/10.1128/mBio.01456-17