Cargando…

Refactoring the Genetic Code for Increased Evolvability

The standard genetic code is robust to mutations during transcription and translation. Point mutations are likely to be synonymous or to preserve the chemical properties of the original amino acid. Saturation mutagenesis experiments suggest that in some cases the best-performing mutant requires repl...

Descripción completa

Detalles Bibliográficos
Autores principales: Pines, Gur, Winkler, James D., Pines, Assaf, Gill, Ryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686537/
https://www.ncbi.nlm.nih.gov/pubmed/29138304
http://dx.doi.org/10.1128/mBio.01654-17