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Combinatorial regulation of the balance between dynein microtubule end accumulation and initiation of directed motility

Cytoplasmic dynein is involved in a multitude of essential cellular functions. Dynein's activity is controlled by the combinatorial action of several regulatory proteins. The molecular mechanism of this regulation is still poorly understood. Using purified proteins, we reconstitute the regulati...

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Detalles Bibliográficos
Autores principales: Jha, Rupam, Roostalu, Johanna, Cade, Nicholas I, Trokter, Martina, Surrey, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686545/
https://www.ncbi.nlm.nih.gov/pubmed/29038173
http://dx.doi.org/10.15252/embj.201797077