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Combinatorial regulation of the balance between dynein microtubule end accumulation and initiation of directed motility
Cytoplasmic dynein is involved in a multitude of essential cellular functions. Dynein's activity is controlled by the combinatorial action of several regulatory proteins. The molecular mechanism of this regulation is still poorly understood. Using purified proteins, we reconstitute the regulati...
Autores principales: | Jha, Rupam, Roostalu, Johanna, Cade, Nicholas I, Trokter, Martina, Surrey, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686545/ https://www.ncbi.nlm.nih.gov/pubmed/29038173 http://dx.doi.org/10.15252/embj.201797077 |
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