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Mucosal IgA Responses: Damaged in Established HIV Infection—Yet, Effective Weapon against HIV Transmission

HIV infection not only destroys CD4(+) T cells but also inflicts serious damage to the B-cell compartment, such as lymphadenopathy, destruction of normal B-cell follicle architecture, polyclonal hypergammaglobulinemia, increased apoptosis of B cells, and irreversible loss of memory B-cell responses...

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Detalles Bibliográficos
Autores principales: Kulkarni, Viraj, Ruprecht, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686557/
https://www.ncbi.nlm.nih.gov/pubmed/29176985
http://dx.doi.org/10.3389/fimmu.2017.01581