EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis

The epidermal growth factor receptor (EGFR), expressed in adrenocorticotrophic hormone (ACTH)–secreting pituitary adenomas causing Cushing disease, regulates ACTH production and corticotroph proliferation. To elucidate the utility of EGFR as a therapeutic target for Cushing disease, we generated tra...

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Detalles Bibliográficos
Autores principales: Araki, Takako, Liu, Xiaohai, Kameda, Hiraku, Tone, Yukiko, Fukuoka, Hidenori, Tone, Masahide, Melmed, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Clinical Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686559/
https://www.ncbi.nlm.nih.gov/pubmed/29264472
http://dx.doi.org/10.1210/js.2016-1053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686559/
https://www.ncbi.nlm.nih.gov/pubmed/29264472
http://dx.doi.org/10.1210/js.2016-1053

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