Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revea...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Endocrine Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686584/ https://www.ncbi.nlm.nih.gov/pubmed/29264514 http://dx.doi.org/10.1210/js.2017-00049 |
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author | Martin, Christopher T. Niewoehner, Catherine B. Burmeister, Lynn A. |
author_facet | Martin, Christopher T. Niewoehner, Catherine B. Burmeister, Lynn A. |
author_sort | Martin, Christopher T. |
collection | PubMed |
description | We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revealed a significantly greater than expected 19% reduction in lumbar spine bone mineral density (BMD) and a 6% reduction in total hip density. Daily alcohol consumption, severe osteoporosis at baseline, and immobilization secondary to transient myelopathy treated with strict bed rest all likely contributed to unexpected BMD findings. |
format | Online Article Text |
id | pubmed-5686584 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Endocrine Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-56865842017-12-20 Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide Martin, Christopher T. Niewoehner, Catherine B. Burmeister, Lynn A. J Endocr Soc Case Report We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revealed a significantly greater than expected 19% reduction in lumbar spine bone mineral density (BMD) and a 6% reduction in total hip density. Daily alcohol consumption, severe osteoporosis at baseline, and immobilization secondary to transient myelopathy treated with strict bed rest all likely contributed to unexpected BMD findings. Endocrine Society 2017-04-24 /pmc/articles/PMC5686584/ /pubmed/29264514 http://dx.doi.org/10.1210/js.2017-00049 Text en Copyright © 2017 Endocrine Society https://creativecommons.org/licenses/by-nc-nd/4.0/ This article has been published under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Martin, Christopher T. Niewoehner, Catherine B. Burmeister, Lynn A. Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide |
title | Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide |
title_full | Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide |
title_fullStr | Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide |
title_full_unstemmed | Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide |
title_short | Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide |
title_sort | significant loss of areal bone mineral density following prolonged bed rest during treatment with teriparatide |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686584/ https://www.ncbi.nlm.nih.gov/pubmed/29264514 http://dx.doi.org/10.1210/js.2017-00049 |
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