Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide

We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revea...

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Autores principales: Martin, Christopher T., Niewoehner, Catherine B., Burmeister, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686584/
https://www.ncbi.nlm.nih.gov/pubmed/29264514
http://dx.doi.org/10.1210/js.2017-00049
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author Martin, Christopher T.
Niewoehner, Catherine B.
Burmeister, Lynn A.
author_facet Martin, Christopher T.
Niewoehner, Catherine B.
Burmeister, Lynn A.
author_sort Martin, Christopher T.
collection PubMed
description We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revealed a significantly greater than expected 19% reduction in lumbar spine bone mineral density (BMD) and a 6% reduction in total hip density. Daily alcohol consumption, severe osteoporosis at baseline, and immobilization secondary to transient myelopathy treated with strict bed rest all likely contributed to unexpected BMD findings.
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spelling pubmed-56865842017-12-20 Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide Martin, Christopher T. Niewoehner, Catherine B. Burmeister, Lynn A. J Endocr Soc Case Report We present of a case of severe osteoporosis with thoracic myelopathy secondary to nontraumatic T8 compression fracture managed nonsurgically with 3.5 months of bed rest. Despite treatment with teriparatide starting at initial presentation, 1-year follow-up dual energy x-ray absorptiometry scan revealed a significantly greater than expected 19% reduction in lumbar spine bone mineral density (BMD) and a 6% reduction in total hip density. Daily alcohol consumption, severe osteoporosis at baseline, and immobilization secondary to transient myelopathy treated with strict bed rest all likely contributed to unexpected BMD findings. Endocrine Society 2017-04-24 /pmc/articles/PMC5686584/ /pubmed/29264514 http://dx.doi.org/10.1210/js.2017-00049 Text en Copyright © 2017 Endocrine Society https://creativecommons.org/licenses/by-nc-nd/4.0/ This article has been published under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Martin, Christopher T.
Niewoehner, Catherine B.
Burmeister, Lynn A.
Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
title Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
title_full Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
title_fullStr Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
title_full_unstemmed Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
title_short Significant Loss of Areal Bone Mineral Density Following Prolonged Bed Rest During Treatment With Teriparatide
title_sort significant loss of areal bone mineral density following prolonged bed rest during treatment with teriparatide
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686584/
https://www.ncbi.nlm.nih.gov/pubmed/29264514
http://dx.doi.org/10.1210/js.2017-00049
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