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Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule
Nicotinamide adenine dinucleotide (NAD+) is an established cofactor for enzymes serving cellular metabolic reactions. More recent research identified NAD+ as a signaling molecule and substrate for sirtuins and poly-adenosine 5′-diphosphate polymerases; enzymes that regulate protein deacetylation and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686634/ https://www.ncbi.nlm.nih.gov/pubmed/29264533 http://dx.doi.org/10.1210/js.2017-00092 |