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Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule

Nicotinamide adenine dinucleotide (NAD+) is an established cofactor for enzymes serving cellular metabolic reactions. More recent research identified NAD+ as a signaling molecule and substrate for sirtuins and poly-adenosine 5′-diphosphate polymerases; enzymes that regulate protein deacetylation and...

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Detalles Bibliográficos
Autores principales: Elhassan, Yasir S., Philp, Andrew A., Lavery, Gareth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686634/
https://www.ncbi.nlm.nih.gov/pubmed/29264533
http://dx.doi.org/10.1210/js.2017-00092