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Effects of Opioid Antagonism on Cerebrospinal Fluid Melanocortin Peptides and Cortisol Levels in Humans

CONTEXT: Hypothalamic proopiomelanocortin (POMC) is processed to α-melanocyte-stimulating hormone, which interacts with the melanocortin antagonist agouti-related protein (AgRP), to regulate energy balance. The POMC-derived opioid peptide β-endorphin (β-EP) also affects feeding behavior via interact...

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Detalles Bibliográficos
Autores principales: Gordon, Rebecca J., Panigrahi, Sunil K., Meece, Kana, Atalayer, Deniz, Smiley, Richard, Wardlaw, Sharon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686644/
https://www.ncbi.nlm.nih.gov/pubmed/29264449
http://dx.doi.org/10.1210/js.2017-00289