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Major Pathophysiology in Prediabetes and Type 2 Diabetes: Decreased Insulin in Lean and Insulin Resistance in Obese

CONTEXT: Lowering of body mass index (BMI) to ≥25 kg/m(2) as obesity by ADA suggests insulin resistance as a major mechanism of impaired glucose metabolism (IGM) in Asians. However, glimepiride, an insulin secretagogue, delayed onset of type 2 diabetes (DM2) from prediabetes (PreDM), indicating decr...

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Detalles Bibliográficos
Autor principal: Kabadi, Udaya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686647/
https://www.ncbi.nlm.nih.gov/pubmed/29264527
http://dx.doi.org/10.1210/js.2016-1116