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Major Pathophysiology in Prediabetes and Type 2 Diabetes: Decreased Insulin in Lean and Insulin Resistance in Obese
CONTEXT: Lowering of body mass index (BMI) to ≥25 kg/m(2) as obesity by ADA suggests insulin resistance as a major mechanism of impaired glucose metabolism (IGM) in Asians. However, glimepiride, an insulin secretagogue, delayed onset of type 2 diabetes (DM2) from prediabetes (PreDM), indicating decr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Endocrine Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686647/ https://www.ncbi.nlm.nih.gov/pubmed/29264527 http://dx.doi.org/10.1210/js.2016-1116 |