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Hypertension and Type 2 Diabetes Are Associated With Decreased Inhibition of Dipeptidyl Peptidase-4 by Sitagliptin

CONTEXT: Patients with diabetes often have comorbidities such as hypertension. It is not known how individual characteristics influence response to dipeptidyl peptidase-4 (DPP4) inhibitors. OBJECTIVE: We tested the hypothesis that individual characteristics, sitagliptin dose, and genetic variability...

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Detalles Bibliográficos
Autores principales: Wilson, Jessica R., Shuey, Megan M., Brown, Nancy J., Devin, Jessica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686657/
https://www.ncbi.nlm.nih.gov/pubmed/29264572
http://dx.doi.org/10.1210/js.2017-00312