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Activation of Sphingolipid Pathway in the Livers of Lipodystrophic Agpat2(−/−) Mice

A several fold increase in triacylglycerol is observed in the livers of lipodystrophic Agpat2(−/−) mice. We have previously reported an unexpected increase in the phosphatidic acid (PA) levels in the livers of these mice and that a few specific molecular species of PA were able to transcriptionally...

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Detalles Bibliográficos
Autores principales: Sankella, Shireesha, Garg, Abhimanyu, Agarwal, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686665/
https://www.ncbi.nlm.nih.gov/pubmed/29264548
http://dx.doi.org/10.1210/js.2017-00157