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Heterogeneity of the Epstein-Barr Virus (EBV) Major Internal Repeat Reveals Evolutionary Mechanisms of EBV and a Functional Defect in the Prototype EBV Strain B95-8

Epstein-Barr virus (EBV) is a ubiquitous pathogen of humans that can cause several types of lymphoma and carcinoma. Like other herpesviruses, EBV has diversified through both coevolution with its host and genetic exchange between virus strains. Sequence analysis of the EBV genome is unusually challe...

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Detalles Bibliográficos
Autores principales: Ba abdullah, Mohammed M., Palermo, Richard D., Palser, Anne L., Grayson, Nicholas E., Kellam, Paul, Correia, Samantha, Szymula, Agnieszka, White, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686732/
https://www.ncbi.nlm.nih.gov/pubmed/28904201
http://dx.doi.org/10.1128/JVI.00920-17