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The potential of interleukin-37 as an effective therapeutic agent in asthma

Interleukin (IL)-37 belongs to the IL-1 cytokine family. It binds to IL-18Rα and recruits the orphan decoy IL-1R8. Emerging evidence shows that IL-37 is a key player in the regulation of inflammation, cellular differentiation, and proliferation. Altered IL-37 expression has been demonstrated in many...

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Detalles Bibliográficos
Autores principales: Zhang, Lina, Zhang, Jie, Gao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686801/
https://www.ncbi.nlm.nih.gov/pubmed/29137646
http://dx.doi.org/10.1186/s12931-017-0675-x