Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors

BACKGROUND: Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set out to analyse the molecular evolution of the HIV-1 subtype B integrase at the inte...

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Detalles Bibliográficos
Autores principales: Meixenberger, Karolin, Yousef, Kaveh Pouran, Smith, Maureen Rebecca, Somogyi, Sybille, Fiedler, Stefan, Bartmeyer, Barbara, Hamouda, Osamah, Bannert, Norbert, von Kleist, Max, Kücherer, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686839/
https://www.ncbi.nlm.nih.gov/pubmed/29137637
http://dx.doi.org/10.1186/s12985-017-0887-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686839/
https://www.ncbi.nlm.nih.gov/pubmed/29137637
http://dx.doi.org/10.1186/s12985-017-0887-1

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