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Isocitrate dehydrogenase mutation in Vibrio anguillarum results in virulence attenuation and immunoprotection in rainbow trout (Oncorhynchus mykiss)

BACKGROUND: Vibrio anguillarum is an extracellular bacterial pathogen that is a causative agent of vibriosis in finfish and crustaceans with mortality rates ranging from 30% to 100%. Mutations in central metabolism (glycolysis and the TCA cycle) of intracellular pathogens often result in attenuated...

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Detalles Bibliográficos
Autores principales: Mou, Xiangyu, Spinard, Edward J., Hillman, Shelby L., Nelson, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686843/
https://www.ncbi.nlm.nih.gov/pubmed/29137620
http://dx.doi.org/10.1186/s12866-017-1124-1